Building Clinical Trial Capacity in Pakistan: From Untapped Potential to Global Research Competitiveness

Authors

  • Ayesha Humayun Shaikh Zayed Postgraduate Medical Institute, Lahore, Pakistan.
  • Salma Malik Institute of Living/Hartford HealthCare, Hartford, CT, USA; University of Connecticut School of Medicine, Farmington, CT, USA.
  • Eman Ayub Shaikh Zayed Postgraduate Medical Institute, Lahore, Pakistan.

DOI:

https://doi.org/10.47489/szmc.v40i3.1081

References

Access to Medicine Foundation. 2024 Access to Medicine Index. Amsterdam: Access to Medicine Foundation; 2024. Available from: https://accesstomedicinefoundation.org/medialibrary/2024-access-to-medicine-index.pdf

Mumtaz H, Haider SMA, Neha F, Saqib M, Nadeem A, Fahim A, et al. Clinical trials landscape in a lower-middle-income country (Pakistan). J Clin Transl Sci. 2024;8(1):e7. https://doi.org/10.1017/cts.2023.701

Hassan W, Ara A. Pakistan has the 2nd highest growth rate in medical sciences research publications for the year 2019-2020: comparison with 46 countries. Proc Pak Acad Sci B Life Environ Sci. 2021;58(3):43-54. https://doi.org/10.53560/PPASB(58-3)661

Viergever RF, Li K. Trends in global clinical trial registration: an analysis of numbers of registered clinical trials in different parts of the world from 2004 to 2013. BMJ Open. 2015;5(9):e008932. https://doi.org/10.1136/bmjopen-2015-008932

Halperin SA, Ye L, MacKinnon-Cameron D, Smith B, Cahn PE, Ruiz-Palacios GM, et al. Final efficacy analysis, interim safety analysis, and immunogenicity of a single dose of recombinant novel coronavirus vaccine (adenovirus type 5 vector) in adults 18 years and older: an international, multicentre, randomised, double-blinded, placebo-controlled phase 3 trial. Lancet. 2022;399(10321):237-48. https://doi.org/10.1016/S0140-6736(21)02753-7

Drug Regulatory Authority of Pakistan. Bio-Study Rules, 2017 (amended by S.R.O. 685(I)/2023). Islamabad: DRAP; 2017. Available from: https://www.dra.gov.pk/wp-content/uploads/2022/02/BiostudyRules2017-4.pdf

World Health Organization. Guidance for best practices for clinical trials. Geneva: World Health Organization; 2024. Available from: https://www.who.int/publications/i/item/9789240097711

Moorthy V, Abubakar I, Qadri F, Ogutu B, Zhang W, Reeder J, et al. The future of the global clinical trial ecosystem: a vision from the first WHO Global Clinical Trials Forum. Lancet. 2024;403(10422):124-6. https://doi.org/10.1016/S0140-6736(23)02798-8

Academy of Medical Sciences, InterAcademy Partnership for Health. Strengthening clinical research capacity in low- and middle-income countries: workshop report. London: Academy of Medical Sciences; 2017. Available from: https://www.interacademies.org/publication/strengthening-clinical-research-capacity-low-and-middle-income-countries

Khan ZA, Muzzamil U, Ahsan K, Khan A, Jawaid M. Barriers of conducting and completing research in Pakistan among doctors: a cross-sectional survey. Pak J Med Sci. 2025;41(3):886-90. https://doi.org/10.12669/pjms.41.3.10424

Moorthy V, Siegfried N, Amuasi J, Li J, Makanga M, Soares-Weiser K, et al. Improving the clinical trial environment and infrastructure: moving from global resolution to action. Lancet Glob Health. 2025;13(4):e608-10. https://doi.org/10.1016/S2214-109X(25)00012-9

Downloads

Published

2026-11-10

How to Cite

1.
Humayun A, Malik S, Ayub E. Building Clinical Trial Capacity in Pakistan: From Untapped Potential to Global Research Competitiveness. Proceedings S.Z.M.C [Internet]. 2026 Nov. 10 [cited 2026 Nov. 10];40(3):256-8. Available from: https://www.proceedings-szmc.org.pk/index.php/szmc/article/view/1081