Using Neutrophil Lymphocyte Ratio to Monitor the Glucose Control in Type 2 Diabetics
DOI:
https://doi.org/10.47489/szmc.v39i4.869Keywords:
Neutrophil-Lymphocyte Ratio, Type 2 Diabetes Mellitus, Glycemic Control, HbA1c, InflammationAbstract
Background: Type 2 Diabetes Mellitus (T2DM) is a significant worldwide and national public health concern, with a high frequency observed in clinical settings. HbA1c is used as a normal for evaluating glycemic control but does not indicate the underlying chronic inflammation connected to T2DM pathophysiology. The NLR, a simple and low-cost inflammatory marker derived from a routine complete blood count, has been associated with T2DM and its complications in numerous populations, but its diagnostic utility in the Pakistani population remains inadequately explored.
Objective: To find the frequency of T2DM in patients presenting to the outpatient department (OPD) and to compare the mean Neutrophil-Lymphocyte Ratio (NLR) between patients with and without T2DM.
Method: This cross-sectional was conducted at King Edward Medical University in Lahore. The sample of 323 consecutive participants visiting the OPD was enlisted. Demographic and clinical information was made. The blood samples were tested on HbA1c and complete blood count. Participants were divided into T2DM (HbA1c 5.7 and above) and Non-Diabetic (HbA1c 5.7 and below). An independent samples t-test was used in the comparison of the means in NLR in the two groups. Gender and age stratification of data was also performed.
Results: T2DM patients were in high frequency in this sample i-e 49.8% (161/323). The average NLR of the T2DM group (2.51 ± 0.84) was also significantly increased over non-diabetic group (1.64 ± 0.54) at <0.001 p-value. This major disparity was maintained in cases where the data were stratified based on age and gender.
Conclusion: The neutrophil-lymphocyte Ratio in the T2DM patients is much higher than that in non-diabetic patients. Simple and cheap NLR is a marker with a close correlation to existence of T2DM.
Corrigendum
In the originally published version of the article listed below, the article title was incorrect.
The incorrect title: “Diagnostic Accuracy of Neutrophil–Lymphocyte Ratio in Predicting Glycemic Control in Type 2 Diabetes Mellitus.”
The correct title is:
“Using Neutrophil Lymphocyte Ratio to Monitor the Glucose Control in Type 2 Diabetics”
This correction pertains only to the article title and does not affect the data, results, interpretation, or conclusions of the study. The online version of the article has been updated accordingly.
Reference
Author(s). Sana Saqib, Mizna Arif, Arsala Rashid, ShawalMir, Husnain Shahid, Hamna Arif .Incorrect article title as originally published. Proceedings of SZMC 2025 ;Volume 39(4):Page numbers. DOI: https://doi.org/10.47489/szmc.v39i4.869
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